I can't wait for The Last Guardian, but in all fairness that won't come out until 2010.
I'm enough of a fanboi (well, fangrrrl I guess) of the Katamari franchise to be psyched for Katamari Forever, although having played the demo I'm feeling a little cranky at their continued abuse of interaction design.
Can't wait for Brutal Legend!
Really really can't wait for Ratchet and Clank: A Crack in Time!
Intrigued by Heavy Rain but not sure if it will actually be any good.
Anyone have Risen yet? From what I can see and have heard, the 360 version is such an ugly, terrible port it's not even worth it. But the PC version sounds great. If you liked the Gothic games, this is apparently a lot like the first.