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Glia: The new frontier in brain science
The current issue of the journal Science (November 5) marks a turning point in research on the brain. This event is fascinating not only for the wealth of new information about how the brain functions and how it fails in mental and neurological illness, but equally as a rare display of a field of science changing course. Such transitions are the lore of scientific history, but rarely do we have the opportunity to witness such pivotal moments in real time.
The journal Science is a premier international journal covering all areas of science, and this issue contains a special section on glia. Glia, in contrast to neurons, are brain cells that do not generate electrical impulses, and there are a lot of them—85 percent of the cells in the brain. Yet, these cells have been largely neglected for 100 years. I call this new frontier of neuroscience "The Other Brain," because we are only now beginning to explore it. The new findings are expanding our concept of information processing in the brain. They are leading rapidly to new treatments for diseases ranging from spinal cord injury to brain cancer to chronic pain, and Alzheimer's disease. And they are overturning a century of conventional thinking about how the brain operates at the most fundamental level.
In the past, glia were understood to support neurons; to feed them and clean up after them, and to respond to brain injury. But these functions were regarded as peripheral to the exciting functions that neurons perform in processing information and storing memories. Consequently, research on glia did not fare well in the fierce competition for the limited grant funding for brain research. Neuroscientists were not trained in glial science, and the standard texts cover glia superficially, if at all. Editors at major journals were not well versed in these odd and very complicated brain cells. As a consequence, glial research was rarely published in high-impact scientific journals. These forces dragged on glial researchers for decades. Now all of this is changing.
Read the rest on Scientific American.
Humans' Big Brains Tied To Chimps' Immunity?
It's a provocative — even astonishing — hypothesis: Could the same set of genes that explains why chimpanzees are protected from some diseases also explain why humans have big brains?
That's what researchers at Stanford University are suggesting.
The genes in question control a type of white blood cell known as natural killer cells, or NK cells.
"They can make a big difference as to whether you get sick, or you don't get sick," says Peter Parham, a professor of cell biology at Stanford. Parham has been studying the genes that control NK cells. And it's not a simple picture — there are a lot of genes involved.
Read the rest of this short article on NPR.
Comment by Jake Farr-Wharton on September 21, 2010 at 7:17pm 

Joan Denoo replied to Joan Denoo's discussion Christianity with and without reductio ad ridiculum fallacy in the group Politics, Economics, and Religion
Joseph P replied to The Big Blue Frog's discussion Gum Chewing and Talking In Class in the group Winning Arguments!© 2013 Atheist Nexus. All rights reserved. Admin: Richard Haynes.


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